For Our Client Hoffman La-Roche, we are looking for a motivated

Analytical Laboratory Technician - Oligonucleotide Development

Location: Basel, Switzerland

Start Date: 01 May 2026

Workload: 100%

Contract Duration: 12 months (possible extension)

Analytical lab tech - Oligonucleotide development

About the Role

Behind every medicine developed or manufactured at Roche is the work of Pharma Global Technical Operations, a global network of 10,000+ employees dedicated to delivering innovative therapies to patients worldwide. Within this community, Pharma Technical Development drives the creation and advancement of new medicines through scientific excellence, creativity, and collaboration.

You will join the Analytical Research & Development group within Synthetic Molecules Technical Development (PTDC)-a team responsible for the analytical method development that enables safe, high?quality drug substances and products for clinical trials.

This role focuses on analytical development for synthetic oligonucleotides, contributing directly to the release and control strategy of novel therapies.

Key Responsibilities

• Perform routine analytical measurements for oligonucleotides, primarily using HPLC (UV / Single Quad MS).
• Plan, execute, and document experiments in close collaboration with a team of five laboratory associates.
• Operate analytical instruments using Empower or OpenLab chromatography data systems.
• Evaluate and interpret data using Genedata or Oligo Analysis Accelerator.
• Develop, optimize, and validate analytical methods for oligonucleotide quality assessment.
• Work in full compliance with GxP standards and internal SOPs.

What You Bring

Must?Haves

• Completed vocational scientific training (e.g., apprenticeship as a Chemical Laboratory Technician, Chemielaborant).
• 2-3 years of experience in the pharmaceutical industry (no Bachelor/Master/PhD).
• Hands?on experience with HPLC and MS (required).
• Strong interest or direct experience in oligonucleotide analytics.
• Quality-focused mindset with strong attention to detail.
• Familiarity with GxP requirements across clinical development phases.
• Proactive, open-minded, team-oriented working style.
• Good command of English (German is a plus).

Nice-to-Haves

• Knowledge of LC?MS applications and instruments.
• Experience with large molecule / biologics analytics.