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We are looking for a Research Associate Mass Spectrometry (m/f/d) (LSW) - BS

Background:

A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Roche.

In Roche’s Pharmaceutical Research and Early Development organization (pRED), we make transformative medicines for patients to tackle some of the world’s toughest unmet healthcare needs. At pRED, we are united by our mission to transform science into medicine. Together, we create a culture defined by curiosity, responsibility and humility, where our talented people are empowered and inspired to bring forward extraordinary life-changing innovation at speed.

This position is located in Lead Discovery, a department within Small Molecule Research which is part of the Therapeutic Modalities function, where the discovery of chemical starting points for further optimization in medicinal chemistry is our primary focus. We closely collaborate with our therapeutic areas and functions to convert hypotheses into innovative therapeutics.

The MS team within the Lead Discovery department is using a wide range of mass spectrometry based approaches for high throughput screening for hit finding, profiling of lead compounds and discovering drug candidate target interaction using cell free assays, cellular systems and tissue samples. This lab based position will primarily focus on deciphering drug candidate target interaction by quantifying endogenous metabolites, lipids, and characterizing protein modification in cellular systems and tissue.

The perfect candidate:

We're searching for a highly skilled individual who has completed an apprenticeship or holds a BS or MS degree in a relevant scientific field. You'll need at least three years of experience in the pharmaceutical or life science industry, bringing hands-on expertise with LC and MS equipment, particularly Triple Quadrupole and/or ToF instruments. This includes proficiency in method development, routine analysis, and troubleshooting. Experience with sample preparation techniques such as homogenization and extraction of tissues and cells is also crucial.

General Information:

• Start date: asap
• latest Start Date: 1.10.25
• Planned duration: 9 months
• Extension (in case of limitation): very likely
• Max. Rate: 50 chf / bill rate max
• Workplace: Basel
• Workload: 100%
• Remote/Home Office: no
• Travel: no
• Team: 7 people
• Department: Mass Spectrometry (PRDFF)
• Working hours: Standard

Tasks & Responsibilities:

• In this lab based role, you will implement, optimize and use LC-MS workflows for metabolites, lipids and proteins, including sample preparation, measurement, data analysis and reporting.
• You will prepare and analyze samples from cell culture and tissue using mass spectrometry.
• You present and discuss your data and findings with colleagues.
• You work collaboratively with your colleagues to contribute to general laboratory operations within the MS team, including instrument maintenance, and troubleshooting.

Must Haves:

• You completed an apprenticeship, or possess a BS or MS degree in a relevant field
• Min 3 years. experience in the pharmaceutical or life science field.
• You have hands-on experience with LC and MS equipment like Triple Quadrupole and/or ToF type instruments, including method development, routine analysis and troubleshooting of instrumentation.
• You bring experience with sample preparation techniques such as homogenization of tissue and cells, extraction or related approaches.
• Fluent in written and verbal English

Nice to Have:

• Experience with analysing recombinant proteins (like intact mass, peptide mapping), proteomics, metabolomics or lipidomics workflows is considered a plus.

Dissatisfied, underchallenged, or ready to discover something new?

What are you waiting for? Apply now, unlock your potential, and strive for greater satisfaction in your career. I will support you with my expertise and guide you through the entire application process. I look forward to meeting you and hearing your story!

MANPOWER AG – Together, we shape your future!