Job ID

REQ-10079216

Jun 16, 2026

Switzerland

Summary

Job Title: Senior Principal Scientist/Principal Scientist I/II, Oncology (RLT)
#LI-Onsite
Location: Basel, Switzerland
Relocation Support: This role is based in Basel, Switzerland. Novartis is unable to offer relocation support: please only apply if accessible.

Shape the future of cancer treatment by driving innovative radioligand therapies from discovery to clinic. As a scientific leader within our Oncology Drug Discovery team in Basel, you will lead cutting-edge preclinical research, designing impactful in vivo studies and collaborating across global, multidisciplinary teams to unlock the potential of next-generation cancer treatments. This role offers a unique opportunity to combine scientific excellence with leadership-mentoring talent, influencing strategy, and translating complex data into meaningful insights that accelerate life-changing therapies for patients worldwide.

About the Role

Key Responsibilities

• Design and lead in vivo studies supporting preclinical evaluation of radioligand therapies
• Drive efficacy, biodistribution, imaging, and mechanism of action studies across oncology programs
• Collaborate with cross-functional teams to advance drug candidates toward clinical development
• Manage external partnerships with contract research organizations and academic collaborators
• Mentor, guide, and develop scientists to strengthen scientific and professional capabilities
• Present data and insights clearly to influence decisions across global research and development teams

Essential Requirements

• Doctor of Philosophy in Pharmacology, Cell Biology, or a related biomedical discipline
• Minimum three years of additional experience in biomedical research within academia or industry
• Strong background in cancer biology with a proven track record of scientific achievement
• Extensive experience designing and managing in vivo oncology studies, including efficacy and pharmacokinetic assessment
• Expertise in ex vivo analysis methods such as flow cytometry, immunofluorescence, immunohistochemistry, or RNA sequencing
• Demonstrated ability to collaborate effectively within multidisciplinary and global research teams
• Excellent communication and presentation skills in English, both written and verbal
• Self-motivated, proactive, and able to independently drive scientific projects forward

Desirable Requirements

• Experience in radioligand therapy development or radiobiology
• Strong understanding of drug development within oncology or related therapeutic areas

This is a dual level posting. The final level and title for this position will be determined following the completion of the candidate evaluation process, based on skills, experience, and organizational needs

Switzerland Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to diversity.inclusion_ch@novartis.com and let us know the nature of your request and your contact information. Please include the job requisition number in your message. 

Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients- lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture

Benefits and Rewards: Learn about all the ways we-ll help you thrive personally and professionally.
Read our handbook (PDF 30 MB)

Division

Biomedical Research

Business Unit

Research

Location

Switzerland

Site

Basel (City)

Company / Legal Entity

C028 (FCRS = CH028) Novartis Pharma AG

Functional Area

Research & Development

Job Type

Full time

Employment Type

Regular

Shift Work

No

Play

Play

00:00

Play

Seek 10 seconds backwards

Seek 10 seconds forward

00:00 / 01:54

Mute

Click to volume controlUse the arrows to control the volume

Settings

Turn on Picture in picture

Show Full screen

Research & Development Biomedical Research Switzerland

Job ID

REQ-10079216

Senior Principal Scientist/Principal Scientist I/II

Apply to Job (link is external)