Technician / Associate - Assay Development & Drug Screening (80-100%)

OVERVIEW InterAx Biotech is among the leading GPCR drug discovery teams in industry. We believe that future advances in drug discovery require deeper understanding of the mechanisms of drug action. The fact that 50% of drug candidates fail due to poor efficacy supports this viewpoint. To understand biological mechanisms, one must map and integrate multiple layers of chemical and biological complexity, from atomic to organism level, and rigorously validate the hypotheses using quantitative in silico models. Such mechanistic modeling is at the core of InterAx – we leverage computational methods and interdisciplinary knowledge to understand the drug effects at different levels of organism complexity. Our in-house expertise includes atomic, molecular, cellular and organism levels, as well as all key stages of drug discovery and early drug development. We leverage unique mathematical models of cell signaling, leading expertise in real-time experimental cellular assays, deep understanding of GPCR pharmacology – the largest class of drug targets, state-of-the-art suite of computational chemistry and machine learning / AI tools, and exceptional medicinal chemistry and drug development expertise. We are currently expanding the InterAx team in Zurich area of Switzerland, and seeking a Technician / Associate Scientist to support our assay development and drug screening activities. The ideal candidate enjoys hands-on work in the lab, is detail-oriented, organized and has a strong interest in optimizing experimental workflows and explore opportunities for automation. This offer gives a chance to join our interdisciplinary, multi-national and innovative team – to contribute to InterAx ambitious journey in developing new technologies, scaling the platform and creating drugs for high-impact diseases areas, all while being a member of a collaborative and inspirational culture. We value respectful communication, knowledge sharing, and supporting each other's growth. If you are a skilled and ambitious scientist seeking to challenge your comfort zone – this position will provide a great opportunity for your growth and development.

PRIMARY RESPONSIBILITIES

• Develop and perform a variety of kinetic cell signaling assays for GPCRs (BRET / FRET-based assays)
• Perform and monitor mammalian cell culture
• Conduct molecular biology techniques including cell transfection and ELISAs for biomarker quantification
• Document, analyze and present experimental data to the team
• Support laboratory organization including management of material orders, inventory and equipment

EDUCATION Master degree in Biology or a related field. Or a Bachelor degree or a completed apprenticeship with 4+ years of relevant experience. Qualifications

• Relevant industry experience in a biotech- or pharma environment is preferred
• Hands-on experience in mammalian cell culture
• Experience with cellular signaling and drug screening assays
• Proficiency with data analysis software such as Microsoft Excel and GraphPad Prism, or R
• Ability to work collaboratively in a cross-functional team
• Good communication skills and fluency in English